Wiskott–Aldrich Syndrome Fund

Wiskott–Aldrich syndrome (WAS) is a rare, inherited primary immune deficiency caused by a genetic mutation affecting clotting and immune function. The condition is present from birth and primarily affects males due to its X-linked inheritance pattern.

WAS is a lifelong condition requiring ongoing management. Individuals are prone to recurrent infections, bleeding complications due to low platelet counts, and inflammatory or autoimmune manifestations. Symptoms commonly include frequent infections, easy bruising or bleeding, eczema, and increased risk of serious immune-related complications. Without consistent medical care and immune-supportive treatment, complications can lead to long-term organ damage and reduced quality of life.

The condition has a significant impact on daily life, often beginning in infancy or early childhood. Ongoing specialty care, regular medical monitoring, immune-supportive therapies, infection prevention strategies, and caregiver involvement are typically required. Frequent healthcare visits and complex care needs place sustained physical, emotional, and financial strain on individuals and their families.