MPS IV Fund

Mucopolysaccharidoses are a group of inherited metabolic diseases caused by the absence or malfunctioning of certain enzymes the body needs to break down molecules called glycosaminoglycans. The result is permanent, progressive cellular damage that affects the individual’s appearance, physical abilities, organ, and system functioning, and, in most cases, mental development. One type is called MPS IV (MPS 4, also known as Morquio Syndrome) and is further classified as Type A or Type B. They are similar in symptoms, but Type A appears to be less severe. People with MPS IV experience spinal nerve compression, clouded corneas, hearing loss, joint stiffness, and restricted breathing.