MPS III Fund

Mucopolysaccharidoses are a group of inherited metabolic diseases caused by the absence or malfunctioning of certain enzymes the body needs to break down molecules called glycosaminoglycans. The result is permanent, progressive cellular damage that affects the individual’s appearance, physical abilities, organ, and system functioning, and, in most cases, mental development. One type is called MPS III (MPS 3, also known as Sanfilippo Syndrome) is marked by severe neurological symptoms that include progressive dementia, aggressive behavior, hyperactivity, seizures, some deafness and vision loss, and an inability to sleep for more than a few hours at a time.