Diffuse Large B-Cell Lymphoma Fund

Diffuse Large B-Cell Lymphoma (DLBCL) is a type of non-Hodgkin lymphoma that beings in the lymphatic system. It affects a specific type of white blood cell that plays a crucial role in the immune system.

Symptoms of DLBCL can develop quickly and may include swollen lymph nodes, fever, weight loss and fatigue.

​​​​Some people may also experience abdominal pain, chest pain, or difficulty breathing if the lymphoma spreads to those areas. DLBCL is aggressive and spreads quickly, but it is also one of the most treatable types of lymphoma when diagnosed early.

DLBCL is the most common type of non-Hodgkin lymphoma in the United States, accounting for about 22-24% of all non-Hodgkin lymphoma cases. Each year, approximately 18,000 to 20,000 new cases of DLBCL are diagnosed in the U.S. DLBCL can affect individuals of any age but is more common in older adults, particularly those over the age of 60. It is slightly more common in men than in women.