Common Variable Immune Deficiency Fund

Common Variable Immune Deficiency (CVID) is a chronic primary immune disorder in which the body’s immune system does not produce sufficient functional antibodies to protect against infections. As a result, individuals often experience recurrent infections of the sinuses, ears, lungs, and other organs, and may also develop autoimmune conditions or chronic inflammation affecting multiple organ systems.

The condition is lifelong and progressive if not adequately treated. Management typically needs ongoing immune-modulating therapy (such as immunoglobulin replacement), infection-prevention strategies, and regular follow-up with specialists. Without consistent treatment and monitoring, people with CVID remain at risk for chronic lung disease, gastrointestinal complications, liver disease, and an increased likelihood of certain malignancies.